Document Type : Research Paper

Authors

1 M.Sc., Department of Environmental Engineering, Faculty of Marine Science and Technology, Tehran North Branch, Islamic Azad University. Tehran, Iran

2 Assist. Professor, Department of Environmental Engineering, and Sciences, Tehran North Branch, Islamic Azad University, Tehran, Iran

Abstract

Hospital wastewater is one of the most infectious and dangerous wastewaters that may contain large amounts of pathogenic microorganisms, dangerous pollutants of various hormones. More than 80 different types of drugs have been found that are not completely eliminated in biological processes and reach the receiving water. In this study, one of the important hospitals of Tehran, in a crowded area with high volume of referrals, was investigated. The purpose of this study was to investigate the possibility of drugs, especially sedative drug compounds, in hospital treated wastewater. For this purpose, instant sampling was carried out three times from the effluent of the hospital wastewater treatment plant and the samples were conditioned using solid phase extraction (SPE) method. The extracted materials were measured by HPLC equipped with UV and FLD detectors, resulting in the identification of various sedatives (including Diazepam, Oxazepam, Lorazepam, Alprazolam Clonazepam, Chlordiazepoxide, and Bromazepam). The mean concentration of sedatives in the January sampling showed that the highest concentration observed for Lorasepam with a mean of 0.15 ng/l and the lowest one for Chlordiazepoxide with a mean of 0.02 ng/l. The highest and lowest concentrations measured in February were 0.15 and 0.02 ng/l for Lorasepam and Chlordiazepoxide respectively.

Keywords

Badejo A. A and Coker A. (2010). Treatment of tertiary hospital wastewater in a pilot-scale natural treatment system (reedbed technology). Res. J. Engin. Appl. Sci., 1, 274-7.
Chimchirian R., Suri R. and Fu H. (2007). Free synthetic and natural estrogen hormones in influent and effluent of three municipal wastewater treatment plants. Water Environ. Res., 79, 969-974.
Dunsmore D. J. (1986). Safety measures for use in outbreaks of communicable diseases. Geneva, World Health Organization.
Emmanuel E., Perrodin Y., Blanchard J. and Vermande P. (2001). Chemical, Biological and ecotoxicological of hospital wastewater. J. Sci. Technol., 2, 31-3.
Franceys R., Pickford J. and Reed R. (1992). A guide to the development of on-site sanitation. Geneva, World Health Organization.
Ghanadzadeh M., Rezaei Ashtiani A., Rajaei M. and Faraz A. (2010). Disposal and filtration of wastewater in hospitals of Markazi Province in 2009. Arak Uni. Med. Sci. J., 13, 100-108.
Kang A. A., Gholami M., Farzadkia M., Javadi Z. and Moayedi A. (2010). Performance evaluation of Iran Universi-ty of medical sciences' hospital wastewater treatment plants. J. Occup. Health, 6, 44-51.
Mahmoudkhani R., Mokhtari Azar A. and Khani M. R. (2012). A survey of tehran hospitals wastewater. Int. J. Environ., 41, 531-538.
Mara D. and Cairncross S. (1989). Guidelines for the safe use of wastewater and excreta in agriculture and aquaculture. Geneva, World Health Organization.
Mara D. (1996). Low-cost urban sanitation. Chichester, England, Wiley.
Pena A., Paulo M., Silva L., Seifrtová M., Lino C. and Solich P. (2010). Tetracycline antibiotics in hospital and municipal wastewaters: a pilot study in Portugal. Anal. Biannual. Chem., 396, 2929-2936.
Pruss A., Giroult E. and Rushbrook P. (1999). Safe management of waste from health-care activities, Gene-va, World Health Organization.
Rezaee A., Ansari M., Khavanian A., Sabzali A. and Aryan M. (2005). Hospital Waste water treatment using an in-tegrated an Anaerobic Aerobic Fixed Film Bioreactor. Am. J. Environ. Sci., 259-263.
Sayadi M. H., Trivedy R. K. and Pathak R. K. (2010). Pollution of pharmaceutical in environment. J. Indust. Pollut. Control, 26(1), 89-94.
Seifrtová M., Pena A., Lino C. and Solich P. (2008). Determination of fluoroquinolone antibiotics in hospital and municipal wastewaters in Coimbra by liquid chromatography with a monolithic column and fluores-cence detection. Anal. Bioanal. Chem., 391, 799-805.
Sharafraz S, Khani M R, Yaghmaeian K. (2007). Quality and quantity survey of hospital wastewater in hor-mozgan province. Iran. J. Environ. Health Sci. Eng., 4, 43-50 [In Persian].
Shariat M. (2001). The principle of water and wastewater treatment. J. Tehran Uni., 6, 124.
WHO (1989). Health guidelines for the use of wastewater in agriculture and aquaculture. Report of a WHO Scientic Group. Geneva, World Health Orga- nization (WHO Technical Report Series, No. 778).
WHO (1996). Fact sheets on environmental sanita on. Epidemic diarrhoeal diseases control. Geneva, World Health Organization.
Wyasu G. and Kure O. A. (2012). Determination of organic pollutants in hospital wastewater and food samples within Ahmadu Bello University Teaching Hospital (Abuth), Shika, Zaria-Nigeria. Adv. Appl. Sci. Res., 3, 1691-1701.